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Contraindications include: Known hypersensitivity to PT-141 or similar peptides History of cardiovascular events such as stroke or myocardial infarction Uncontrolled hypertension Pregnancy or breastfeeding Active liver or kidney disease If you have any chronic health conditions or are taking other medications, speak with a qualified provider before starting PT-141
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Methods Animals Animal experiments were performed with adherence to all national and local guidelines and regulations, the Guide for the Care and Use of Laboratory Animals 25 , and the ARRIVE guidelines, and with the approval of the Institutional Animal Care and Use Committee at The University of Texas Medical Branch (UTMB)
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Propionyl-L-carnitine increases cellular carnitine content, thereby allowing free fatty acid transport into the mitochondria
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