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Injection Site Reactions: When using injectable forms, some patients may experience injection site reactions such as pain, swelling, or redness

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This is likely placebo effect or vasodilation response, as tissue B12 saturation requires 24-48 hours

In women, virilization (development of male features) can occur and may be irreversible if the drug is not discontinued promptly.Other Side Effects: Other potential side effects include nausea, vomiting, insomnia, headache, rapid weight gain (swelling), and changes in skin color

Plantar fasciitis causing heel pain has, in rare cases, been reported as a symptom of vitamin D deficiency