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Contraindications: Do not use in patients with a personal or family history of medullary thyroid carcinoma or in patients with MEN2 (Multiple Endocrine Neoplasia syndrome type 2)
From a research perspective, understanding why some patients respond dramatically while others see modest benefit remains an active area of investigation
In the trials that led to Wegovys approval for weight management, people with obesity or overweight who used 2.4 mg of semaglutide once weekly lost an average of nearly 15% of their body weight over a 68-week treatment period
One review found people with type 2 diabetes who followed a keto diet lowered their A1C levelsa measure of blood sugar over several months
To understand the effects of GLP-1RAs on binge eating behaviors, researchers undertook a systematic review and meta-analysis
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