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Seoud, M
Clinical practice guidelines suggest several scenarios where dose modification may be appropriate: Persistent gastrointestinal symptoms lasting beyond the first week of a new dose level may warrant extending that dose phase by an additional 2-4 weeks before further escalation
large RCT outcome data is lacking for direct injection
Putting the numbers in context A 22.7% mean weight reduction in a 100kg person represents a loss of approximately 22.7kg
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