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Comparison with other clinical forms of diabetes
Recently reported real-world and comparative analyses have raised questions about differential cardiovascular outcomes versus semaglutide in selected datasets
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As of 2022, GLP-1RAs have been recommended as first-line treatments, along with SGLT-2 inhibitors, for patients with T2DM and cardiovascular disease in American Diabetes Associations Standards of Medical Care in Diabetes (248, 249)
In a cohort study with a total of 29,363 patients, out of whom 3,997 were diagnosed with colorectal adenoma, the association between risk of colorectal adenomas and intake of specific carotenoids was analyzed, showing that lycopene intake was negatively correlated with adenoma risk (Jung et al., 2013)
