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Same units, different milligrams, because the concentration changed

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Table 3: Prolia / Xgeva (denosumab) and Jakafi / Opzelura (ruxolitinib) dual brands 8 Source: CRA Research and Analysis, 2023 Differential value and price alignment with dual brands In some cases significant differences in dosing can lead to differences in cost across indications, if cost is imputed on a parity cost-per-unit basis

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