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doi: 10.3390/cancers15010272 6 WangHZhuTYangKXuCZhangZLiuG

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Tips for managing abnormal skin sensations Wear loose-fitted clothing Shower or bathe with lukewarm water Place a cool compress over the burning or sensitive skin areas Ask your healthcare provider before taking pain relievers or topical analgesics If abnormal skin sensations are severe or persistent, contact your healthcare provider

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Reverse-phase LC (RP-LC) is most commonly used Separates GLP-1 peptides, impurities, and variants Minimizes matrix interference and ion suppression Key Insight: Proper chromatographic separation improves downstream identification and quantification accuracy

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