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These quality specifications ensure the reconstitution solvent does not introduce endotoxin, microbial, particulate, or chemical contamination into reconstituted research compound solutions

This provides adequate systemic exposure while remaining within commonly researched dose ranges

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For influenza A, there are at least 18 hemagglutinin (HA) and 12 neuraminidase (NA) subtypes, with group 1 and group 2 species sharing only ~37% sequence homology for HA and NA proteins and only ~25% sequence homology with influenza B species (reviewed in ref

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