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No, AOD-9604 is not FDA-approved and is available only for research purposes
173 At the molecular level, gene modulation techniques, including siRNA- and shRNA-mediated silencing of efflux transporter genes (e.g., ABCB1, ABCG2), as well as CRISPR/Cas9-based gene editing, have successfully resensitized tumor cells to chemotherapy in preclinical models
The thiol groups are also of great importance in substrate binding of enzymes, in metal-sulfur clusters in proteins (e.g
Biomedicine Pharmacother
Neuroscience research 55, 223233, doi: 10.1016/j.neures.2006.03.004 (2006)
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