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Even when insulin is used, these classes of medications still provide benefits. Joanna Khatib In a meta-analysis, Khatib and colleagues assessed major adverse CV events from eight recent CV outcome trials for SGLT2 inhibitors, GLP-1 receptor agonists and DPP-IV inhibitors: DECLARE, EMPA-REG, EXSCEL, HARMONY, LEADER, SUSTAIN-6, EXAMINE and SAVOR-TIMI 53
59 Burg et al synthesized modified peptidomimetic glutathione analogs of these EAGSH compounds, which were hypothesized to be stabler against peptidase-mediated dissolution
For example, our pipeline and drug surveillance teams continuously monitor new drug launches, formulations and indications of GLP-1s
Science 356 , eaam7263 (2017)
Imagine if the mortality benefit of semaglutide continues to expand over 10 years and we can deliver this intervention at scale
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