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Does reduced IGF-1R signaling in igf1r mice alter aging
For the subgroup analysis of the time to the first occurrence of the main 5-component composite endpoint, the pre-specified Cox regression model also included an interaction between treatment group and the subgroup of interest, with the interaction P values evaluated using a score test
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Possible explanations include dehydration from gastrointestinal side effects like nausea, vomiting, or diarrhoea, and metabolic changes associated with the medication
Steinbacher, P., & Eckl, P
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