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20 DaviesMFaerchLJeppesenOKPaksereshtAPedersenSDPerreaultLet al
Theranostics 12 , 27412757 (2022)
Kumar said you can expect manufacturing and storage to be easier and cheaper for a pill like this, so once someone starts, theyre less likely to face the shortages we saw after Wegovy and Zepbound launched. This could make orforglipron more accessible to many people, Kumar noted
Preclinical data further indicate that liraglutide activates the SIRT1 signaling cascade, suppresses atrophy-related genes, and upregulates myogenic differentiation factors, thereby protecting against obesity-induced muscle atrophy and contributing to structural muscle integrity [14, 16]
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