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KF: Conceptualization, Methodology, Resources, Supervision, Writing review & editing
13 But in April 2025, when the final rule was published, CMS (under a new administration) noted that they had decided not to finalize that portion of the proposed rule
[1] Bi-Amino Injections clinical rationale draws on pharmacokinetic evidence that intravenous arginine produces a sharp plasma peak followed by biphasic clearance, whereas citrulline bypasses splanchnic arginase activity, undergoes efficient renal conversion back to arginine, and sustains substrate availability for nitric-oxide synthase several hours beyond the initial infusion