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found that in sheep ovarian granulosa cells, LPS treatment suppresses GPX4 expression, resulting in lipid peroxide accumulation and decreased mitochondrial membrane potential, while restoration of GPX4 expression reverses LPS-induced ferroptosis (61)

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a , HT1080 OE GFP-GPX4 WT and HT1080 OE GFP-GPX4 R152H were treated with 4 M RSL3, 30 g/ml cycloheximide, and 100 M a-Tocopherol for 0, 2, 4, or 6 hours before Western Blot analysis of GPX4 and GADPH

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