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Balancing out moderate coffee consumption with a diet that promotes glutathione levels is the best option

Alghamdi BS, AboTaleb HA (2020) Melatonin improves memory defects in a mouse model of multiple sclerosis by up-regulating cAMP-response element-binding protein and synapse-associated proteins in the prefrontal cortex

Indoleamine 2, 3-dioxygenase 1 (IDO1), indoleamine 2, 3-dioxygenase 2 (IDO2), and tryptophan-2, 3-dioxygenase (TDO) catalyze the rate-limiting step of tryptophan catabolism in the kynurenine pathway to consume tryptophan and produce kynurenine