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Cell Metab

Safety: Preclinical studies show low toxicity across animal models (PubMed 32334036)

Its important to understand that these dosing parameters come from rat studies and cannot be directly translated to human use without proper clinical trials

[5] In a landmark 2014 study, knocking down NNMT in fat and liver protected mice against diet-induced obesity by increasing cellular energy expenditure, and raised adipose SAM and NAD levels

It has also been shown to lower homocysteine levels, a molecule linked to inflammation and cognitive decline, with longitudinal studies linking optimal B12 levels with improved cognitive function, mood and reduced risk of neurodegenerative disease