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doi:10.1155/2020/6718985
UK Chief Medical Officers' guidelines recommend: Strength activities on at least 2 days per week, targeting major muscle groups to stimulate muscle protein synthesis and preserve lean tissue Cardiovascular activity for at least 150 minutes weekly of moderate-intensity exercise (or 75 minutes of vigorous activity) Daily movement and reducing sedentary behaviour to support overall energy expenditure Adequate protein intake is important for muscle preservation
More importantly, the hazard ratio for major adverse cardiovascular events (including cardiovascular death, myocardial infarction, stroke, or hospitalization for unstable angina) for the pooled tirzepatide groups versus glargine was 0.74 (95% CI 0.511.08), suggesting no increased cardiovascular risk with tirzepatide compared to insulin glargine
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