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Glutathione is the liver's primary tool for "Phase II detoxification." In this phase, the liver attaches a glutathione molecule to a toxin, making it water-soluble so it can be excreted through bile or urine
To prioritize biologically relevant candidates and based on our hypothesis that the evolved protease favors caspase substrates, we cross-referenced the hits with the MerCASBA database 56 of known caspase substrates, identifying potential cleavage events associated with cell death
An overview of the unfolded protein response (Upr) and autophagy pathways in human viral oncogenesis
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