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Side Effects of GLP-1 Patches Since patches havent been widely tested, the only clues we have about possible risks come from the supplement ingredients they contain: Possible side effects L-carnitine: nausea, diarrhea, fishy odor [24] Glutamine: bloating [12] Berberine: stomach upset, nausea, constipation [25] Pomegranate: digestive issues [26] Resveratrol: digestive issues, headaches [27] B-vitamins: flushing, nerve irritation at high doses [28] Chromium: mood changes, insomnia, headaches [29] More serious risks L-carnitine: may raise TMAO levels linked to heart disease [30] High-dose glutamine: may worsen seizures [31] Berberine: interacts with many prescription drugs