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Hydroquinone carries a 25% risk of ochronosis (paradoxical darkening) with prolonged use above 4% concentration
PMID 21268762
Table of Inhibitors of Oxidative Phosphorylation Energy from Cytosolic NADH In contrast to oxidation of mitochondrial NADH, cytosolic NADH when oxidized via the electron transport system gives rise to two equivalents of ATP if it is oxidized by the glycerol phosphate shuttle (see above) and three equivalents of ATP if it proceeds via the malate-aspartate shuttle
Keep in mind that is the calculated power output over time
Additionally, there was no family history of similar symptoms or central nervous system or other systemic tumors
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