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Table of Contents Understanding How Wegovy Works in Your Body Wegovy (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist licensed by the MHRA for chronic weight management in adults with obesity or overweight with weight-related comorbidities

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Its spurred by a vast neurochemical web of interactions

The glucagon receptor activation is the unique third piece it directly increases energy expenditure and promotes the breakdown of stored fat in the liver and adipose tissue