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Moreover, we demonstrated that neuroinflammatory mechanisms including gasdermin-mediated pyroptosis play important roles in the neurodegenerative process in GCLC-KO mice
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E., & Overduin, J
A contribution of NTS astrocytes to the appetite suppression caused by acute GLP-1R agonists also seems possible from evidence showing (1) expression of GLP-1Rs in this cell type, (2) functional responses of astrocytes to exendin-4 and liraglutide, and (3) negation of appetite suppression from administration of exendin-4 into the NTS when astrocyte metabolism is selectively inhibited in this region [56]
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