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Bypassing the digestive system and the liver ensures 100% absorption or bioavailability of all nutrients, compared orally consumed supplementation, as many nutrients are destroyed during metabolism
Intravenous B-12 carries significantly higher anaphylaxis risk and is not standard practice in most clinics
In addition to TfR, the other extensively investigated receptors and transporters for brain targeting are LDL receptor and glucose transporter
Mix product well in 1-2 cups of liquid (water, juice, etc.) immediately before consumption
Ultimately, more research studies with larger sample sizes will need to be conducted before more conclusive claims can be made about the role, if any, of MTHFR variants in disease
