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II: 24h, GSH-Px activity
The 4-substituted benzyl chain formed a hydrophobic bond with F424 and F427, while the C3-(4-fluorophenyl) amino side chain occupied a lipophilic pocket made up of F392, L409, and V417 (Figures 7A,B)
This damage is called oxidative stress and it leads to chronic inflammation and health problems including diseases like cancer
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Mller Y, Lengacher L, Friscourt F, Quairiaux C, Stoppini L, Magistretti PJ, Lengacher S, Finsterwald C (2024) Epileptiform activity in brain organoids derived from patient with glucose transporter 1 deficiency syndrome
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