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Not only can a deficiency in vitamin B12 cause schizophrenia, but vitamins B6 and B9 can also contribute to the condition, and symptoms can be reduced by supplementing these vitamins alongside antipsychotics (70)

Omega-3 fatty acid (2000 mg EPA+DHA in 3:2 ratio) supplementation increased brain glutathione

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In vitro experiments showed that 10 ng/mL IGF-1 LR3 could increase the proliferation rate of breast cancer MCF-7 cells by three times, and reduce the sensitivity of chemotherapy drugs (such as paclitaxel) by 40%

While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control