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K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
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The study by Elkind-Hirsch et al
Multi-stimuli platforms, including cascade-responsive constructs While single-stimulus systems respond to either pH or redox cues, tumors present multiple environmental abnormalities simultaneously, and sequential multi-stimulus responsiveness can further refine tumor selectivity by requiring nanoparticles to encounter a series of conditions in the correct order before releasing drug
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