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Your starting dose will depend on which dose you were previously taking

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Even though lower doses are presumably safer, using them would still require a new pre-IND safety justification, dose-range toxicology studies, and possibly a new manufacturing lot release. That would add ~12 years of delay

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The FDAs Office of Generic Drugs monitors whether a first-filer has forfeited its exclusivity rights through failure to market, failure to obtain tentative approval, or other triggering events before it begins

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A calorie deficit is a fancy way of saying youre eating fewer calories than your body is burning throughout the day

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[Glutathione-S-transferase and glutathione in the liver and blood of rats poisoned by [PMID: 7448078] Laboratory literature summary: [Glutathione-S-transferase and glutathione in the liver and blood of rats poisoned by thioacetamide]

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