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With this analysis it appears plausible that hindbrain activationvia the AP and, potentially, the NTSis communicated to the lateral parabrachial nucleus (lPBN), which then activates further neuronal populations (e.g., in the amygdala)
The response is cumulative, building across the 4 doses and continuing into the weeks after the final injection
Medicare maintains it as durable medical equipment billed under Part B
In a subgroup analysis, changes in predicted probabilities were analyzed by an MMRM based on on-treatment data
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