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Potential roles: Syngene CRDMO work in large molecules, analytics, and development support for current and next-gen GLP1s
In various models, GLP-1 was also able to stimulate beta cell replication [although this was dependent on the age of the islet cells (92)] as well as neogenesis (from ductal precursors) (93) and importantly GLP-1 also inhibited apoptosis of human beta cells, induced for instance by fatty acids or cytokines (94)
They lower blood glucose by triggering the pancreas to release more insulin and by suppressing a hormone called glucagon
It also slows gastric emptying , meaning food stays in your stomach longer, helping you feel fuller for an extended period
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