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Orlistat (Alli / Xenical): Blocks fat absorption in the digestive system, but can cause unpleasant gastrointestinal side effects

Liu M, Kong XY, Yao Y, Wang XA, Yang W, Wu H, Li S, Ding JW, Yang J

10.2174/0109298673325682241114162014 69 FurukawaS.FujitaT.ShimabukuroM.IwakiM.YamadaY.NakajimaY.et al (2017)

Initial therapy with the combination of Januvia and metformin provided significant improvements in A1C, FPG, and 2-hour PPG compared to placebo, to metformin alone, and to Januvia alone (Table 5, Figure 1)