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Semaglutide (not semiglutide), also known as the skinny shot, belongs to the GLP-1 receptor agonist class of medications
Genes with de novo variants in 2 patients were prioritised for follow-up, and replication was performed using a targeted next-generation-sequencing panel in 71 individuals with neonatal diabetes
The lag-1 gene contains multiple consensus LAG-1/CSL binding sites [16], and along with the distal germline restricted accumulation pattern, suggests the possibility that LAG-1 accumulation occurs through a positive transcriptional loop via GLP-1 signaling
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Semaglutide has been used longer and works by mimicking a hormone called GLP-1
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