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doi:10.1056/NEJMoa2032183 Lincoff AM, BrownFrandsen K, Colhoun HM, Deanfield J, Emerson SS, Esbjerg S, HardtLindberg S, Hovingh GK, Kahn SE, Kushner RF, Lingvay I, Oral TK, Michelsen MM, Plutzky J, Torne CW, Ryan DH

Exp Clin Endocrinol (1983) 81(3):26372

Direct quotation from the 2023 OMA guidelines: "Anti-obesity medication selection should be driven by efficacy data, individual patient response, side-effect profile, and access rather than by any single algorithm." OMA clinical practice guidelines are available at pubmed.ncbi.nlm.nih.gov

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These criteria help ensure a clean signal from the data while still maintaining a clinically relevant study population