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Bi-allelic loss-of-function variants in CFAP58 cause flagellar axoneme and mitochondrial sheath defects and asthenoteratozoospermia in humans and mice
This can help improve stamina and reduce tiredness during exercise
For most people the fix is simple: drink water deliberately throughout the day, and consider an electrolyte source if your intake is low or your side effects are pulling fluids out
Hospitals, including Ben Taub and Lyndon B
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