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Mean Weight Loss in Pivotal Trials Maximum Dose, ITT Population Tirzepatide 15 mg weekly SURMOUNT-1, NEJM 2022 n=2,539 PMID 35658024 22.5% body weight 72 weeks Tirzepatide 10 mg weekly SURMOUNT-1, NEJM 2022 19.5% body weight 72 weeks Tirzepatide vs Semaglutide head-to-head SURPASS-2, NEJM 2021 n=1,879 +47% more weight loss vs sema Semaglutide 2.4 mg weekly (comparison) STEP-1, NEJM 2021 14.9% body weight 68 weeks Frequently Asked Questions Common questions about NexLife and tirzepatide Is NexLife legit for tirzepatide

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While internal cellular support begins immediately, visible results like improved skin radiance usually take 8 to 12 weeks

For the replication analysis, we tested for association between the EHR-derived BMI % and the genotype, including covariates