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The information below reflects USP standards, manufacturer prescribing information, published trial protocols, and self-reported community sources
Constitutive activation of NRF2 has been considered as a resistance mechanism to chemo or radiation therapy because the NRF2-mediated antioxidant response eliminates therapy-induced ROS, thereby promoting cell survival
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Subsequent work by Heffernan and coworkers (2001) confirmed the peptides effects in obese mouse models, with chronic administration associated with reduced body weight gain and decreased adiposity without concurrent changes in food intake
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