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Surface of a cell and the peptide, if it's available, will bind to that receptor and then set in motion a kind of bucket brigade, a sort of conveyor belt of cellular processes
Veena J, Srikumar BN, Raju TR, Shankaranarayana Rao BS
For instance, FOXO4-D-Retro-Inverso (DRI) induces the selective apoptosis of senescent cells by inhibiting the FOXO4-p53 interaction 34
J Med Chem 58:73707380 Gotfredsen CF, Molck AM, Thorup I et al (2014) The human GLP-1 analogs liraglutide and semaglutide: absence of histopathological effects on the pancreas in nonhuman primates
A quantitative metabolomics study revealed that pancreatic stellate cells (PSCs) critically contribute to PDAC metabolic reprogramming by supporting the cancer cell tricarboxylic acid (TCA) cycle and lipid biosynthesis through autophagy-dependent alanine secretion [349]
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