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It may also be prescribed when oral supplementation is not possible or not sufficient, for example after certain gastrointestinal surgeries or in severe malabsorption
Oral formulations rely on passive absorption but, owing to the pathophysiology of the condition, patients with pernicious anaemia will only absorb around 1% of an orally administered dose[23]
Vitamin B12 functions as a cofactor in cellular metabolism but possesses no thermogenic properties and does not directly influence adipose tissue metabolism or fat burning
The clinical program failed
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