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Senescent tumor cells secrete a TGF--enriched senescence-associated secretory phenotype (SASP), which activates AKT-mTOR signaling, reshapes the TME, and promotes malignant progression under therapeutic pressure

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Patients should be taught about three major treatments for severe kidney disease, which are peritoneal dialysis (a treatment that uses the lining of your abdomen to filter your blood), hemodialysis (a treatment where a machine filters your blood) and kidney transplants, when their kidney disease reaches stage 4

Serving patients from Cardiff, Swansea, Newport, Monmouthshire, Bridgend and across South Wales

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