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Stephen Bloom of Hammersmith Hospital in London discovered that injecting GLP-1 into rats brains caused a significant reduction in appetite

[134] [144] [145] Once FosB is sufficiently overexpressed, it induces an addictive state that becomes increasingly more severe with further increases in FosB expression

Due to the huge difference in single excretion cycles, the full course span of the two drugs is entirely different

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