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Retatrutide is still investigational and only available in clinical trials
The key clinical question you need to ask right now is not whether GLP-1s are overhyped
Classic Symptoms Polyuria: frequent urination Polydipsia: increased thirst Polyphagia: increased hunger Fatigue and blurred vision may also occur Many patients are diagnosed during routine screening Metabolic Features Central obesity is common Insulin resistance is the major underlying problem Metabolic syndrome often coexists Hypertension and dyslipidemia are frequently present Skin Clues Acanthosis nigricans at neck and axilla suggests insulin resistance Skin tags may be present Recurrent skin infections can occur in poorly controlled disease Microvascular Complications Retinopathy: blurred vision, retinal damage in long-standing disease Nephropathy: microalbuminuria is an early sign
3 Proper nutrition is critically important for a strong immune system
A 26-week randomized trial reported that tesamorelin reduced visceral fat and improved aspects of the lipid profile in adults with HIV-associated abdominal-fat accumulation. A later analysis divided participants according to their visceral-fat response
