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[4] Deponte, M
Available to buy in the UK from Peptides Lab UK, FOXO4-DRI is one of the most extensively studied senolytic research peptides in cellular senescence biology, with a rapidly growing published literature base spanning senescent fibroblast elimination, vascular ageing, Leydig cell senescence, chondrocyte biology, keloid scar research, cancer cell senescence, and structural NMR characterisation of the FOXO4p53 interaction
They have an incretin action, reducing glucose plasmatic levels through the stimulation of insulin secretion by the pancreatic beta-cells and the concomitant inhibition of glucagon secretion by alpha-cells
It also inhibits melanin production, helping to lighten hyperpigmentation and brighten the skin tone
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