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Since heart rate parameters often reflect changes in autonomic function, one meta-analysis analysed 64 studies to assess differences in heart rate parameters in ME/CFS (329)
At the same time, the majority of included studies were conducted in specific geographic regions (e.g., United States, Denmark, China), which may not represent the global population
Much longer and the medication might accumulate excessively or take too long to clear
While the exact mechanism is not fully understood, it is believed that the medications impact on the bodys metabolism and endocrine system could play a role
Metabolism: Clinical and Experimental, 46 (4), 410413
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