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glucagon receptor activation carries a theoretical hyperglycaemia risk, though phase 2 data suggest this is counterbalanced
The Nature Communications MD checklist is provided as Supplementary Table 11
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However, the heterogeneity of study design and inclusion criteria, modest cohort sizes, differences in reported outcomes (e.g., histologic characteristics), lack of fibrosis improvement, and uncertain long-term benefits and safety have limited interpretation of their therapeutic safety and efficacy
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