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Darker skin (reduced synthesis)
Originally used to treat type 2 diabetes, GLP1 medications are now also widely used for weight management
Probiotics may help with the gastrointestinal adjustment that occurs when stopping GLP-1 therapy
If irritation continues to occur, apply an over-the-counter itch cream, preferably with hydrocortisone, or discontinue use entirely
Understanding these differences helps contextualize why some users report local reactions and others report gastrointestinal ones
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