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The question of when to take retatrutide in terms of the day of the week and time of day follows the same general principles as other once-weekly injectables, based on trial protocols: Choose a consistent day each week (for example, every Monday) to maintain regularity

Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells

This precision-focused approach helps distinguish patients who may benefit most from medication versus those who may achieve prediabetes reversal through intensive lifestyle intervention alone

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doi: 10.1186/s12967-025-06635-8 50