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We hypothesised that the reported brainstem transcriptomic changes might reflect modulation of NTS Ppg neuron activity downstream of GIPR antagonism in the hypothalamus and therefore tested the effect of GIPR-antag on mice with ablated NTS Ppg neurons (Ppg NTS-Abl ) generated by bilateral stereotactic injection of AAV-DTA into the NTS of Ppg-Cre or control mice (Cre-negative mice receiving AAV-DTA into the NTS) (Fig

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Su principal funcin consiste en favorecer el transporte de los cidos grasos hasta el interior de las mitocondrias, donde pueden ser utilizados para la produccin de energa celular

Viruses require iron for replication and often obtain this nutrient by targeting the iron-rich organelles, mitochondria, and lysosomes, disrupting their function, including ferritinophagy and myelination (Chang et al., 2015)

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