Blood pressure increases become more consistent, potassium shifts become measurable, and glucose perturbations may require pharmacologic management in patients with prediabetes or diabetes
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Oral formulations work for many patients but typically require higher doses to achieve blood levels comparable to injections, and some patients experience gastrointestinal side effects from higher oral volumes
Digestive side effects of GLP-1s include nausea, bloating, vomiting, constipation, diarrhea, belching, indigestion and more, outlined in Figure 3 of this article and Table 2 of this article