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They showed that EED deletion in mouse neural stem/progenitor cells by conditional knockout of EED driven by hGFAP-Cre inhibited neurogenesis in vivo , with a strong decrease of neuroblasts and immature neurons (DCX + cells), as well as in vitro , with reduced proliferation of primary neural stem/progenitor cells in neurosphere cultures
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Tham kho thm Dng glutathione lu di c an ton khng
reported that, different from in vitro assay, as l-cysteine is present in micromolar concentrations in the intracellular environment, the activity of -glutamyl phosphate reductase (GPR) encoded by PRO2 in eukaryotes or proA in prokaryotes must be shut off to allow -GC formation from -glutamyl phosphate [12]
