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-Discontinuation due to adverse events: 4.1% (4 mg) vs 11.3% (12 mg) vs 4.9% placebo -Dysesthesia reported in 12.5% at 12 mg vs 0.9% placebo Open questions: -The 4 mg dose gave nearly 20% weight loss with a single dose escalation step and a discontinuation rate indistinguishable from placebo
That said, the emerging biology surrounding GLP-1 pathways has opened a genuinely compelling scientific frontier
Phase 4: Bulk order (weeks 5-8) Negotiate pricing and terms for your full order based on demonstrated quality from the trial batch
DermNet NZ
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