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PD actually involves dysfunction in dopamine metabolism in many parts and regions of the brain, including synthesis, secretion, transport, reuptake, elimination, and receptor binding of DA (16)
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Recent advances have focused on overcoming the limitations of PEGylation, often referred to as the PEG dilemma, where the PEG layer extending circulation time can hinder cellular uptake at the target site
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Both the mRNA and protein levels of Nrf2 and HO-1 were significantly elevated in the DAPA-treated si-Nrf2 mice compared with the si-Nrf2 group (Fig
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